Below are the 3 most recent journal entries recorded in thermalcycle's InsaneJournal:

Thursday, July 15th, 2010
7:52 pm	Gradient Thermal Cycler Must Have Features Read the entire article : PCR Thermal Cycler With the breakneck pace of the technological upgrades in our modern society, it is no wonder that the science driving a pcr thermal cycler, also known as a thermocycler, is ever improving. Whether you are looking to purchase for the first time or seeking an upgrade in laboratory equipment, the following are tips to guide you in the right direction. 1. Performing DNA testing, you should be able to switch temperatures at a quick pace to keep you running the tests you need done. Minimal PCR Thermal Cycler Equilibration Time Once your pcr thermal cycler gets to the appropriate temperature, the instrument will need additional time to settle and stabilize into a precise zone. Look for models which provide short stabilization intervals to increase your throughput. Although it may seem trivial, this small step can save you countless hours over the lifetime of the instrument. Precise Thermal Cycler Block Temperature Uniformity Regardless of the location where temperature measurements are taken across the block, the reading should be the same. Ensure your pcr thermal cycler has tight tolerance levels for its block uniformity. 4. Interchangeable Thermal Cycler Blocks with multiple block formats The needs of a laboratory can be very dynamic. Be careful to ensure that your thermocycler has the capability to change out the block. If your block fails or your lab needs to change to a different block format, you can simply purchase a new block rather than an entirely new instrument. This simple step could potentially save you thousands of dollars. 5. This feature will undoubtedly save your laboratory tons of time by allowing you to test samples at multiple temperatures on a single run. This gradient thermal cycler feature is a must have. 6. Laboratory space is limited. Be sure you won't be stuck with a hulking mahcine in your lab. 7. Adequate Memory for Programming It can be a pain programming the same protocol over and over again. It is not only a time consuming ordeal, but it also opens your laboratory up to an increased risk of user errors in testing. Save yourself the headache by getting the proper amount of memory. Read the entire article : PCR Thermal Cycler (Comment on this)
Monday, July 5th, 2010
8:55 pm	Thermal Cycler Hybaid Sprint The PCR Sprint Thermal Cycler remains the instrument of choice for low throughput labs requiring sub-ambient thermal cycling. It employs robust peltier technology with heating rates up to 3°C/sec with excellent uniformity and accuracy. Each thermal cycler includes a standard heated lid providing users with oil free running. It offers 0.2 milliliter x 24 well or 0.5 milliliter x 20 well thermal cycler block arrangements. A huge benefit provided by the Hybaid Sprint PCR thermal cycler is the interchangable blocks. When requirements change, they are easily switched out! The Hybaid company which has been known for its PCR Sprint thermal cycler and its PCR Express thermal cycler for years, has released its own version of block gradient thermal cycler. With an emphasis placed on maintaining temperature uniformity, Hybaid offers gradient blocks which can be fitted to the PCR thermal cycler and is capable of running gradient as well as normal thermal cycler testing. Hybaid claims the unique feature of having internal thermistors which take extremely accurate internal measurements of the true sample temperature. There are dwell time differentials between the annealing temperatures usually when determining gradient protocols for your thermal cycler. Hybaid combats this issue with its system for controlling temperature known as Active Tube as well as software which combine to accurately determine internal sample temperatures. The combination of these solutions allow for thermal cycler annealing temperature percision to within 0.5 degrees Celcius. Video of Thermal Cycler Material science is constantly noteworthy in regards to the conversations on new technologies. When it comes to silicates, synthetic polymers, or even Bucky balls, the options of molecular makeup is seemingly unbounded which can address any issue. When engineers run out of ideas or encounter serious obstacles for improving the mechanical workings of a particular design, they frequently look at the materials they're working with to see if they can be altered to improve an existing product. Manufacturers of thermal cyclers have experimented with different metals to improve the effectiveness of their products. It has been discovered that silver-gold thermal cycler blocks work quite optimally for pcr testing applications, although many blocks are made from aluminum which is covered a surface which is hard-anodized of corundum cystals. . If you like this article, check out for about Thermo Scientific Hybaid PCR Sprint Thermal Cycler (Comment on this)
Friday, July 2nd, 2010
12:49 am	Eppendorf Mastercycler Thermal Cycler Eppendorf Scientific was first to market with a single block gradient thermal cycler, the Mastercycler® Gradient. This thermal cycler has the ability of performing tests over 12 separate temperatures at the same time across the single block within 20 degrees celcius. Eppendorf also offers a non-gradient version called the Mastercycler Personal. Both units feature cross-compatible personal memory cards and a universal block that can hold either 0.2ml or 0.5ml tubes and PCR plates. As other companies are beginning to appreciate the advantages of the gradient design, Eppendorf Scientific is looking for ways to break away from the pack. Along with this revolutionary family of thermal cyclers, Eppendorf also offers their patented line of accessories, the MasterTaq tool kit, and Taq Polymerase. The MasterTaq kit allows for PCR enhancing which gives lab technicials increased repeatablity and robustness in their PCR reactions. "It is our goal to be a company that provides, one-stop shopping" for our customers' PCR needs," says Vincent Prezioso, product manager for Eppendorf. "We plan on launching many new instruments and reagents for PCR in the coming year." Learn More About the Eppendorf Mastercycler Thermal Cycler. (Comment on this)